Forty four In addition, anergic cells Typically keep an increased susceptibility to apoptosis Except anti-apoptotic proteins for instance BCL2 are overexpressed, as is the case for CLL cells.45 In fact, most main therapeutic innovations taking place in the last decade are connected to the inhibition of BCR and BCL2-mediated signaling. https://annw753oxf0.blog5star.com/profile