Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors inside the central nervous program, conolidine modulates alternate molecular targets. A Science Developments analyze identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability.... https://whatischronicpain32097.thezenweb.com/not-known-factual-statements-about-conoldine-alternative-natural-pain-relief-76012062